Pirates vs. Cardinals Game Preview: Live MLB Prediction, Odds & Picks
🟢•Next update in: 12 minutes from now
Pirates vs. Cardinals preview (May 21). Updated every 15 minutes with current odds (Pirates -122), Bryan Reynolds props & pitching matchup: Braxton Ashcraft vs. Dustin May (probable).
Today's Data Snapshot
| Market Source: | FanDuel |
|---|---|
| Primary Prediction: | Total O 7 |
| Key Player Prop: | Bryan Reynolds Over 0.5 RBIs |
| Probable Pitchers: | Braxton Ashcraft (RHP; 3.09 ERA) vs. Dustin May (RHP; 4.81 ERA) |



Pittsburgh Pirates
25-24
CARD

St. Louis Cardinals
28-20

GAME PREDICTIONS
PREDICTED GAME OUTCOME
CHANCE TO WIN
44%
Model Picks
Total
Total O 7
Insights provided by the SportsGrid betting model
LATEST PLAYER PROPS
LATEST PLAYER PROPS
Frequently Asked Questions
What are the latest odds and run line for Pittsburgh Pirates vs. St. Louis Cardinals?
The Pittsburgh Pirates are favored by 1.5 runs on the run line (-1.5), while the St. Louis Cardinals are underdogs +1.5 runs. The moneyline is Pittsburgh Pirates -122 and St. Louis Cardinals +104. The over/under is set at 7 runs.
Who is projected to win Pittsburgh Pirates vs. St. Louis Cardinals, and what are the win probabilities?
The model projects the Pittsburgh Pirates to win by 0.6 runs. Win probability is 56% for the Pittsburgh Pirates and 44% for the St. Louis Cardinals.
Who are the probable starting pitchers for Pittsburgh Pirates vs. St. Louis Cardinals?
For this matchup, Pittsburgh Pirates is expected to start Braxton Ashcraft (RHP; 3.09 ERA), while St. Louis Cardinals will likely go with Dustin May (RHP; 4.81 ERA). Pitching matchups can change due to injuries, rest days, or strategic decisions.
What are the best bets for Pittsburgh Pirates vs. St. Louis Cardinals (run line, moneyline, total)?
The SportsGrid model's top game pick is Total O 7. The projected margin supports this pick.
What are the top player prop picks for Pittsburgh Pirates vs. St. Louis Cardinals?
Top player props include Bryan Reynolds Over 0.5 RBIs, Brandon Lowe Over 0.5 RBIs, Oneil Cruz Over 0.5 RBIs. These are highlighted as strong value plays by the SportsGrid model.





























