Astros vs Cubs Final Score — May 22
Odds & predictions, free picks, prop bets, and injury updates
Houston Astros
4
Apple TV+
Chicago Cubs
2
GAME PREDICTIONS
Model Picks
Cubs
Cubs -1.5
Total
Total O 7
Insights provided by the SportsGrid betting model
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Frequently Asked Questions
What are the latest odds and run line for Houston Astros vs. Chicago Cubs?
The Chicago Cubs are favored by 1.5 runs on the run line (-1.5), while the Houston Astros are underdogs +1.5 runs. The moneyline is Houston Astros +120 and Chicago Cubs -142. The over/under is set at 7 runs.
What are the best bets for Houston Astros vs. Chicago Cubs (run line, moneyline, total)?
The SportsGrid model's top game pick is Total O 7. The projected margin supports this pick.
