Guardians vs. Tigers Game Preview: Live MLB Prediction, Odds & Picks
🟢•Next update in: 10 minutes from now
Guardians vs. Tigers preview (May 21). Updated every 15 minutes with current odds (Tigers -120), Brayan Rocchio props & pitching matchup: Joey Cantillo vs. Casey Mize (probable).
Today's Data Snapshot
| Market Source: | FanDuel |
|---|---|
| Primary Prediction: | Total O 7 |
| Key Player Prop: | Brayan Rocchio Over 0.5 RBIs |
| Probable Pitchers: | Joey Cantillo (LHP; 3.58 ERA) vs. Casey Mize (RHP; 2.43 ERA) |



Cleveland Guardians
29-22
CLEG

Detroit Tigers
20-30

GAME PREDICTIONS
PREDICTED GAME OUTCOME
CHANCE TO WIN
54%
Model Picks
Total
Total O 7
Insights provided by the SportsGrid betting model
LATEST PLAYER PROPS
LATEST PLAYER PROPS

CLE

DET
05/21 ·1:10 PM

CLE

DET
05/21 ·1:10 PM

CLE

DET
05/21 ·1:10 PM
Frequently Asked Questions
What are the latest odds and run line for Cleveland Guardians vs. Detroit Tigers?
The Detroit Tigers are favored by 1.5 runs on the run line (-1.5), while the Cleveland Guardians are underdogs +1.5 runs. The moneyline is Cleveland Guardians +102 and Detroit Tigers -120. The over/under is set at 7 runs.
Who is projected to win Cleveland Guardians vs. Detroit Tigers, and what are the win probabilities?
The model projects the Detroit Tigers to win by 0.3 runs. Win probability is 54% for the Detroit Tigers and 46% for the Cleveland Guardians.
Who are the probable starting pitchers for Cleveland Guardians vs. Detroit Tigers?
For this matchup, Cleveland Guardians is expected to start Joey Cantillo (LHP; 3.58 ERA), while Detroit Tigers will likely go with Casey Mize (RHP; 2.43 ERA). Pitching matchups can change due to injuries, rest days, or strategic decisions.
What are the best bets for Cleveland Guardians vs. Detroit Tigers (run line, moneyline, total)?
The SportsGrid model's top game pick is Total O 7. The projected margin supports this pick.
What are the top player prop picks for Cleveland Guardians vs. Detroit Tigers?
Top player props include Brayan Rocchio Over 0.5 RBIs, Matt Vierling Over 0.5 RBIs, Spencer Torkelson Over 0.5 RBIs. These are highlighted as strong value plays by the SportsGrid model.





























